{"id":9796,"date":"2025-06-13T01:03:33","date_gmt":"2025-06-12T17:03:33","guid":{"rendered":"https:\/\/www.51malin.com\/index.php\/archives\/9796"},"modified":"2025-06-13T01:03:33","modified_gmt":"2025-06-12T17:03:33","slug":"%e7%a0%94%e7%a9%b6dbu%e8%8b%84%e5%9f%ba%e6%b0%af%e5%8c%96%e9%93%b5%e7%9b%90%e4%b8%8e%e5%85%b6%e4%bb%96%e5%8a%a9%e5%89%82%e7%9a%84%e5%8d%8f%e5%90%8c%e6%95%88%e5%ba%94","status":"publish","type":"post","link":"https:\/\/www.51malin.com\/index.php\/archives\/9796","title":{"rendered":"\u7814\u7a76DBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0\u4e0e\u5176\u4ed6\u52a9\u5242\u7684\u534f\u540c\u6548\u5e94"},"content":{"rendered":"

DBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0\u4e0e\u5176\u4ed6\u52a9\u5242\u7684\u534f\u540c\u6548\u5e94\u7814\u7a76<\/strong><\/p>\n

\n

\u4e00\u3001\u5f15\u5b50\uff1a\u5316\u5b66\u53cd\u5e94\u4e2d\u7684\u201c\u642d\u5b50\u6587\u5316\u201d<\/h3>\n

\u5728\u6211\u4eec\u65e5\u5e38\u751f\u6d3b\u4e2d\uff0c\u5e38\u5e38\u4f1a\u542c\u5230\u201c\u642d\u5b50\u201d\u8fd9\u4e2a\u8bcd\u2014\u2014\u670b\u53cb\u4e4b\u95f4\u4e92\u4e3a\u642d\u5b50\uff0c\u6253\u6e38\u620f\u8981\u627e\u642d\u5b50\uff0c\u505a\u996d\u4e5f\u8981\u627e\u642d\u5b50\u3002\u800c\u5728\u5316\u5b66\u9886\u57df\uff0c\u5c24\u5176\u662f\u6709\u673a\u5408\u6210\u4e2d\uff0c\u5176\u5b9e\u4e5f\u5b58\u5728\u4e00\u79cd\u201c\u642d\u5b50\u6587\u5316\u201d\u3002\u67d0\u4e9b\u8bd5\u5242\u5355\u72ec\u4f7f\u7528\u65f6\u6548\u679c\u5e73\u5e73\uff0c\u4f46\u4e00\u65e6\u4e0e\u53e6\u4e00\u79cd\u7269\u8d28\u201c\u8054\u624b\u201d\uff0c\u4fbf\u80fd\u53d1\u6325\u51fa1+1>2\u7684\u795e\u5947\u6548\u679c\u3002<\/p>\n

\u4eca\u5929\u6211\u4eec\u8981\u804a\u7684\u5c31\u662f\u8fd9\u6837\u4e00\u4e2a\u201c\u642d\u5b50\u7ec4\u5408\u201d\u2014\u2014DBU\uff081,8-\u4e8c\u6c2e\u6742\u53cc\u73af[5.4.0]\u5341\u4e00\u78b3-7-\u70ef\uff09\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0<\/strong>\u4e0e\u5176\u4ed6\u52a9\u5242\u4e4b\u95f4\u7684\u534f\u540c\u6548\u5e94\u3002\u8fd9\u4e0d\u4ec5\u662f\u4e00\u4e2a\u5b66\u672f\u8bdd\u9898\uff0c\u66f4\u662f\u73b0\u4ee3\u7eff\u8272\u5316\u5b66\u548c\u9ad8\u6548\u50ac\u5316\u53cd\u5e94\u4e2d\u7684\u91cd\u8981\u7ec4\u6210\u90e8\u5206\u3002<\/p>\n

\u522b\u770b\u540d\u5b57\u62d7\u53e3\uff0c\u5b83\u53ef\u662f\u5728\u5f88\u591a\u6709\u673a\u53cd\u5e94\u4e2d\u626e\u6f14\u7740\u201c\u50ac\u5316\u5242\u4e2d\u7684\u50ac\u5316\u5242\u201d\u7684\u89d2\u8272\u3002\u800c\u5f53\u6211\u4eec\u628a\u5b83\u4e0e\u4e00\u4e9b\u5408\u9002\u7684\u52a9\u5242\u642d\u914d\u5728\u4e00\u8d77\u65f6\uff0c\u5f80\u5f80\u80fd\u591f\u6253\u5f00\u4e00\u7247\u65b0\u7684\u53cd\u5e94\u5929\u5730\u3002<\/p>\n

\n

\u4e8c\u3001DBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0\u7684\u57fa\u672c\u4ecb\u7ecd<\/h3>\n

\u9996\u5148\uff0c\u6211\u4eec\u6765\u8ba4\u8bc6\u4e00\u4e0b\u8fd9\u4f4d\u4e3b\u89d2\u2014\u2014DBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0<\/strong>\u3002<\/p>\n

1. \u5316\u5b66\u7ed3\u6784\u4e0e\u6027\u8d28<\/h4>\n\n\n\n\n\n\n\n\n\n\n\n
\u5c5e\u6027<\/th>\n\u63cf\u8ff0<\/th>\n<\/tr>\n<\/thead>\n
\u5316\u5b66\u540d\u79f0<\/td>\nDBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0<\/td>\n<\/tr>\n
\u5206\u5b50\u5f0f<\/td>\nC\u2081\u2087H\u2082\u2086N\u2082Cl<\/td>\n<\/tr>\n
\u5206\u5b50\u91cf<\/td>\n\u7ea6294.86 g\/mol<\/td>\n<\/tr>\n
\u5916\u89c2<\/td>\n\u767d\u8272\u6216\u7c7b\u767d\u8272\u7c89\u672b<\/td>\n<\/tr>\n
\u6eb6\u89e3\u6027<\/td>\n\u6613\u6eb6\u4e8e\u6c34\u3001\u3001DMF\u7b49\u6781\u6027\u6eb6\u5242<\/td>\n<\/tr>\n
pH\u503c\uff081%\u6c34\u6eb6\u6db2\uff09<\/td>\n\u7ea69.5~10.5<\/td>\n<\/tr>\n
\u7a33\u5b9a\u6027<\/td>\n\u5728\u5e38\u6e29\u4e0b\u7a33\u5b9a\uff0c\u907f\u514d\u5f3a\u9178\u73af\u5883<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

DBU\u672c\u8eab\u662f\u4e00\u79cd\u5f3a\u78b1\u6027\u975e\u4eb2\u6838\u78b1\uff0c\u5e7f\u6cdb\u7528\u4e8e\u6709\u673a\u5408\u6210\u4e2d\u4f5c\u4e3a\u78b1\u6216\u76f8\u8f6c\u79fb\u50ac\u5316\u5242\u3002\u5f53\u5b83\u4e0e\u82c4\u57fa\u6c2f\u5316\u94f5\u7ed3\u5408\u540e\uff0c\u5f62\u6210\u7684\u5b63\u94f5\u76d0\u4e0d\u4ec5\u80fd\u63d0\u9ad8\u5176\u6eb6\u89e3\u6027\u548c\u7a33\u5b9a\u6027\uff0c\u8fd8\u80fd\u589e\u5f3a\u5176\u50ac\u5316\u6027\u80fd\uff0c\u5c24\u5176\u9002\u7528\u4e8e\u4e24\u76f8\u4f53\u7cfb\u4e2d\u7684\u53cd\u5e94\u3002<\/p>\n

2. \u5e94\u7528\u573a\u666f<\/h4>\n
    \n
  • Michael\u52a0\u6210<\/strong><\/li>\n
  • Knoevenagel\u7f29\u5408<\/strong><\/li>\n
  • \u916f\u4ea4\u6362\u53cd\u5e94<\/strong><\/li>\n
  • \u4e0d\u5bf9\u79f0\u50ac\u5316<\/strong><\/li>\n
  • \u7eff\u8272\u6eb6\u5242\u4f53\u7cfb\u4e2d\u7684\u53cd\u5e94\u8c03\u63a7<\/strong><\/li>\n<\/ul>\n
    \n

    \u4e09\u3001\u52a9\u5242\u767b\u573a\uff1a\u5b83\u4eec\u90fd\u662f\u8c01\uff1f\u53c8\u80fd\u5e72\u5565\uff1f<\/h3>\n

    \u6240\u8c13\u201c\u52a9\u5242\u201d\uff0c\u5c31\u662f\u90a3\u4e9b\u5728\u53cd\u5e94\u4e2d\u4e0d\u76f4\u63a5\u53c2\u4e0e\u4e3b\u53cd\u5e94\uff0c\u4f46\u53ef\u4ee5\u6539\u5584\u53cd\u5e94\u6761\u4ef6\u3001\u63d0\u5347\u6548\u7387\u3001\u63a7\u5236\u526f\u4ea7\u7269\u7684\u201c\u5e55\u540e\u82f1\u96c4\u201d\u3002<\/p>\n

    \u5e38\u89c1\u7684\u52a9\u5242\u5305\u62ec\uff1a<\/p>\n\n\n\n\n\n\n\n\n\n
    \u52a9\u5242\u7c7b\u578b<\/th>\n\u5e38\u89c1\u79cd\u7c7b<\/th>\n\u4e3b\u8981\u4f5c\u7528<\/th>\n<\/tr>\n<\/thead>\n
    \u8868\u9762\u6d3b\u6027\u5242<\/td>\nCTAB\u3001SDS\u3001Triton X-100<\/td>\n\u6539\u5584\u754c\u9762\u5f20\u529b\uff0c\u4fc3\u8fdb\u4e24\u76f8\u6df7\u5408<\/td>\n<\/tr>\n
    \u76f8\u8f6c\u79fb\u50ac\u5316\u5242<\/td>\nPEG\u3001PEG-400\u3001\u51a0\u919a<\/td>\n\u63d0\u9ad8\u79bb\u5b50\u8fc1\u79fb\u901f\u7387\uff0c\u52a0\u5feb\u53cd\u5e94\u52a8\u529b\u5b66<\/td>\n<\/tr>\n
    \u6c22\u952e\u4f9b\u4f53\/\u53d7\u4f53<\/td>\n\u5c3f\u7d20\u3001\u7518\u6cb9\u3001DMSO<\/td>\n\u8c03\u8282\u5206\u5b50\u95f4\u76f8\u4e92\u4f5c\u7528<\/td>\n<\/tr>\n
    \u7eff\u8272\u6eb6\u5242<\/td>\n\u6c34\u3001\u79bb\u5b50\u6db2\u4f53\u3001<\/td>\n\u63d0\u5347\u73af\u4fdd\u6027\uff0c\u964d\u4f4e\u6bd2\u6027<\/td>\n<\/tr>\n
    \u91d1\u5c5e\u76d0\u7c7b<\/td>\nLiCl\u3001NaI\u3001ZnCl\u2082<\/td>\n\u5f71\u54cd\u7535\u8377\u5206\u5e03\uff0c\u6539\u53d8\u53cd\u5e94\u8def\u5f84<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u8fd9\u4e9b\u52a9\u5242\u867d\u7136\u5404\u81ea\u529f\u80fd\u4e0d\u540c\uff0c\u4f46\u5728\u4e0eDBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0\u914d\u5408\u4f7f\u7528\u65f6\uff0c\u5f80\u5f80\u4f1a\u8868\u73b0\u51fa\u4ee4\u4eba\u60ca\u559c\u7684\u534f\u540c\u6548\u5e94\u3002<\/p>\n

    \n

    \u56db\u3001\u534f\u540c\u6548\u5e94\u89e3\u6790\uff1a\u4e0d\u662f\u7b80\u5355\u7684\u201c1+1=2\u201d\uff0c\u800c\u662f\u201c1+1=3\u201d<\/h3>\n

    \u8ba9\u6211\u4eec\u901a\u8fc7\u51e0\u4e2a\u5178\u578b\u7684\u53cd\u5e94\u6848\u4f8b\uff0c\u6765\u770b\u770bDBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0\u4e0e\u4e0d\u540c\u52a9\u5242\u4e4b\u95f4\u7684\u201c\u5316\u5b66\u7231\u60c5\u6545\u4e8b\u201d\u3002<\/p>\n

    1. Michael\u52a0\u6210\u4e2d\u7684CTAB\u534f\u540c\u6548\u5e94<\/h4>\n

    \u5728\u7ecf\u5178\u7684Michael\u52a0\u6210\u53cd\u5e94\u4e2d\uff0cDBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0\u672c\u8eab\u5c31\u53ef\u4ee5\u4f5c\u4e3a\u78b1\u548c\u76f8\u8f6c\u79fb\u50ac\u5316\u5242\uff0c\u4f46\u5982\u679c\u52a0\u5165\u5c11\u91cf\u7684CTAB\uff08\u5341\u516d\u70f7\u57fa\u4e09\u7532\u57fa\u6eb4\u5316\u94f5\uff09<\/strong>\uff0c\u53cd\u5e94\u901f\u7387\u53ef\u4ee5\u663e\u8457\u63d0\u5347\u3002<\/p>\n\n\n\n\n\n\n
    \u6761\u4ef6<\/th>\n\u8f6c\u5316\u7387 (%)<\/th>\n\u53cd\u5e94\u65f6\u95f4 (h)<\/th>\n\u526f\u4ea7\u7269\u6bd4\u4f8b<\/th>\n<\/tr>\n<\/thead>\n
    \u5355\u72ecDBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0<\/td>\n78<\/td>\n12<\/td>\n15%<\/td>\n<\/tr>\n
    + CTAB\uff080.1 eq\uff09<\/td>\n98<\/td>\n6<\/td>\n<5%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u539f\u56e0\u5206\u6790\uff1a<\/strong>
    \nCTAB\u4f5c\u4e3a\u4e00\u79cd\u9633\u79bb\u5b50\u8868\u9762\u6d3b\u6027\u5242\uff0c\u80fd\u5728\u6c34-\u6709\u673a\u4e24\u76f8\u754c\u9762\u5f62\u6210\u80f6\u675f\u7ed3\u6784\uff0c\u5c06\u53cd\u5e94\u5e95\u7269\u96c6\u4e2d\u5230\u754c\u9762\u533a\u57df\uff0c\u4ece\u800c\u63d0\u9ad8\u4e86DBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0\u5bf9\u5e95\u7269\u7684\u63a5\u89e6\u6548\u7387\uff0c\u52a0\u901f\u4e86\u53cd\u5e94\u8fdb\u7a0b\u3002<\/p>\n

    \ud83d\udca1\u5c0f\u8d34\u58eb\uff1a\u5982\u679c\u4f60\u5728\u505aMichael\u52a0\u6210\uff0c\u4e0d\u59a8\u8bd5\u8bd5\u8fd9\u4e2a\u201cCTAB+DBU\u76d0\u201d\u7684\u7ec4\u5408\u62f3\uff0c\u7701\u65f6\u53c8\u7701\u5fc3\uff01<\/p>\n

    \n

    2. Knoevenagel\u7f29\u5408\u4e2d\u7684PEG-400\u52a0\u6301<\/h4>\n

    Knoevenagel\u7f29\u5408\u662f\u6709\u673a\u5408\u6210\u4e2d\u5e38\u7528\u7684C-C\u952e\u6784\u5efa\u65b9\u6cd5\u4e4b\u4e00\u3002\u5728\u8fd9\u4e2a\u53cd\u5e94\u4e2d\uff0cDBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0\u4f5c\u4e3a\u78b1\u548c\u50ac\u5316\u5242\u8868\u73b0\u4f18\u5f02\uff0c\u4f46\u5f53\u52a0\u5165PEG-400<\/strong>\uff08\u805a\u4e59\u4e8c\u9187400\uff09\u65f6\uff0c\u6548\u679c\u66f4\u4e0a\u4e00\u5c42\u697c\u3002<\/p>\n\n\n\n\n\n\n
    \u6dfb\u52a0\u5242<\/th>\n\u8f6c\u5316\u7387 (%)<\/th>\n\u53cd\u5e94\u6e29\u5ea6 (\u2103)<\/th>\n\u662f\u5426\u9700\u8981\u52a0\u70ed<\/th>\n<\/tr>\n<\/thead>\n
    \u65e0\u6dfb\u52a0\u5242<\/td>\n65<\/td>\n\u5ba4\u6e29<\/td>\n\u5426<\/td>\n<\/tr>\n
    + PEG-400\uff0810 wt%\uff09<\/td>\n95<\/td>\n\u5ba4\u6e29<\/td>\n\u5426<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u673a\u5236\u89e3\u8bfb\uff1a<\/strong>
    \nPEG-400\u5177\u6709\u826f\u597d\u7684\u6c22\u952e\u80fd\u529b\uff0c\u80fd\u591f\u7a33\u5b9a\u4e2d\u95f4\u4f53\uff0c\u5e76\u4e14\u4f5c\u4e3a\u201c\u6db2\u6001\u8f7d\u4f53\u201d\u5e2e\u52a9\u5e95\u7269\u66f4\u597d\u5730\u6eb6\u89e3\u548c\u6269\u6563\u3002\u540c\u65f6\uff0c\u5b83\u8fd8\u80fd\u8c03\u8282\u4f53\u7cfb\u7c98\u5ea6\uff0c\u4f7fDBU\u76d0\u66f4\u5bb9\u6613\u53d1\u6325\u4f5c\u7528\u3002<\/p>\n

    \ud83c\udf89\u7ed3\u8bba\uff1a\u5ba4\u6e29\u5c31\u80fd\u641e\u5b9a\uff0c\u7eff\u8272\u73af\u4fdd\uff0c\u8c01\u4e0d\u559c\u6b22\uff1f<\/p>\n

    \n

    3. \u916f\u4ea4\u6362\u53cd\u5e94\u4e2d\u7684LiCl\u52a9\u653b<\/h4>\n

    \u5728\u916f\u4ea4\u6362\u53cd\u5e94\u4e2d\uff0c\u4f20\u7edf\u6761\u4ef6\u4e0b\u5f80\u5f80\u9700\u8981\u8f83\u9ad8\u7684\u6e29\u5ea6\u548c\u8f83\u957f\u7684\u53cd\u5e94\u65f6\u95f4\u3002\u800cDBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0\u4e0eLiCl<\/strong>\u7684\u7ec4\u5408\uff0c\u5219\u53ef\u4ee5\u5728\u6e29\u548c\u6761\u4ef6\u4e0b\u5b9e\u73b0\u9ad8\u6548\u7684\u916f\u4ea4\u6362\u3002<\/p>\n\n\n\n\n\n\n
    \u6dfb\u52a0\u5242<\/th>\n\u8f6c\u5316\u7387 (%)<\/th>\n\u6e29\u5ea6 (\u2103)<\/th>\n\u65f6\u95f4 (h)<\/th>\n<\/tr>\n<\/thead>\n
    \u65e0\u6dfb\u52a0<\/td>\n40<\/td>\n80<\/td>\n8<\/td>\n<\/tr>\n
    + LiCl\uff080.2 eq\uff09<\/td>\n92<\/td>\n60<\/td>\n4<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u4e3a\u4ec0\u4e48\u6709\u6548\uff1f<\/strong>
    \nLi\u207a\u79bb\u5b50\u80fd\u591f\u4e0e\u916f\u6c27\u914d\u4f4d\uff0c\u524a\u5f31\u916f\u952e\u7684\u7535\u5b50\u5bc6\u5ea6\uff0c\u4ece\u800c\u66f4\u5bb9\u6613\u88ab\u4eb2\u6838\u8bd5\u5242\u653b\u51fb\u3002\u8fd9\u79cd\u201c\u8f6f\u5316\u201d\u4f5c\u7528\u8ba9DBU\u76d0\u5728\u66f4\u4f4e\u6e29\u5ea6\u4e0b\u4e5f\u80fd\u9ad8\u6548\u50ac\u5316\u53cd\u5e94\u3002<\/p>\n

    \"\"<\/p>\n\n\n\n\n\n\n
    \u6dfb\u52a0\u5242<\/th>\n\u8f6c\u5316\u7387 (%)<\/th>\n\u6e29\u5ea6 (\u2103)<\/th>\n\u65f6\u95f4 (h)<\/th>\n<\/tr>\n<\/thead>\n
    \u65e0\u6dfb\u52a0<\/td>\n40<\/td>\n80<\/td>\n8<\/td>\n<\/tr>\n
    + LiCl\uff080.2 eq\uff09<\/td>\n92<\/td>\n60<\/td>\n4<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u4e3a\u4ec0\u4e48\u6709\u6548\uff1f<\/strong>
    \nLi\u207a\u79bb\u5b50\u80fd\u591f\u4e0e\u916f\u6c27\u914d\u4f4d\uff0c\u524a\u5f31\u916f\u952e\u7684\u7535\u5b50\u5bc6\u5ea6\uff0c\u4ece\u800c\u66f4\u5bb9\u6613\u88ab\u4eb2\u6838\u8bd5\u5242\u653b\u51fb\u3002\u8fd9\u79cd\u201c\u8f6f\u5316\u201d\u4f5c\u7528\u8ba9DBU\u76d0\u5728\u66f4\u4f4e\u6e29\u5ea6\u4e0b\u4e5f\u80fd\u9ad8\u6548\u50ac\u5316\u53cd\u5e94\u3002<\/p>\n

    \ud83e\uddea\u6e29\u99a8\u63d0\u793a\uff1a\u60f3\u8981\u8282\u80fd\u53c8\u9ad8\u6548\u7684\u916f\u4ea4\u6362\uff1fLiCl\u662f\u4e2a\u597d\u5e2e\u624b\uff01<\/p>\n

    \n

    \u4e94\u3001\u534f\u540c\u6548\u5e94\u80cc\u540e\u7684\u79d1\u5b66\u903b\u8f91<\/h3>\n

    \u90a3\u4e48\uff0cDBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0\u4e0e\u5404\u79cd\u52a9\u5242\u4e4b\u95f4\u4e3a\u4ec0\u4e48\u4f1a\u53d1\u751f\u534f\u540c\u6548\u5e94\u5462\uff1f\u6211\u4eec\u53ef\u4ee5\u4ece\u4ee5\u4e0b\u51e0\u4e2a\u89d2\u5ea6\u6765\u7406\u89e3\uff1a<\/p>\n

    1. \u754c\u9762\u8c03\u63a7\u7406\u8bba<\/strong><\/h4>\n

    \u52a9\u5242\u5982CTAB\u3001Triton X-100\u7b49\u80fd\u964d\u4f4e\u754c\u9762\u5f20\u529b\uff0c\u4fc3\u8fdb\u4e24\u76f8\u6df7\u5408\uff0c\u4f7f\u5f97DBU\u76d0\u66f4\u5bb9\u6613\u5c06\u5e95\u7269\u4ece\u6c34\u76f8\u8f6c\u79fb\u5230\u6709\u673a\u76f8\uff0c\u6216\u8005\u53cd\u4e4b\u3002<\/p>\n

    2. \u5fae\u73af\u5883\u6784\u5efa<\/strong><\/h4>\n

    PEG\u3001\u79bb\u5b50\u6db2\u4f53\u7b49\u52a9\u5242\u53ef\u5728\u5c40\u90e8\u5f62\u6210\u201c\u5fae\u53cd\u5e94\u5668\u201d\uff0c\u63d0\u4f9b\u4e00\u4e2a\u66f4\u9002\u5408\u53cd\u5e94\u8fdb\u884c\u7684\u5fae\u73af\u5883\uff0c\u6bd4\u5982\u66f4\u9ad8\u7684\u6781\u6027\u3001\u66f4\u5f3a\u7684\u6c22\u952e\u7f51\u7edc\u7b49\u3002<\/p>\n

    3. \u79bb\u5b50\u8c03\u63a7\u673a\u5236<\/strong><\/h4>\n

    \u50cfLiCl\u3001NaI\u8fd9\u7c7b\u91d1\u5c5e\u76d0\u53ef\u4ee5\u901a\u8fc7\u79bb\u5b50\u914d\u4f4d\u3001\u7535\u8377\u5c4f\u853d\u7b49\u65b9\u5f0f\uff0c\u5f71\u54cd\u5e95\u7269\u7684\u6d3b\u6027\u548cDBU\u76d0\u7684\u50ac\u5316\u884c\u4e3a\u3002<\/p>\n

    4. \u52a8\u529b\u5b66\u4fc3\u8fdb<\/strong><\/h4>\n

    \u52a9\u5242\u7684\u5b58\u5728\u5f80\u5f80\u53ef\u4ee5\u52a0\u5feb\u53cd\u5e94\u7684\u52a8\u529b\u5b66\u8fc7\u7a0b\uff0c\u7f29\u77ed\u8bf1\u5bfc\u671f\uff0c\u63d0\u9ad8\u53cd\u5e94\u901f\u7387\u3002<\/p>\n

    \n

    \u516d\u3001\u5b9e\u9645\u5e94\u7528\u6848\u4f8b\uff1a\u7eff\u8272\u5408\u6210\u4e2d\u7684\u5178\u8303<\/h3>\n

    DBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0\u4e0e\u52a9\u5242\u7684\u534f\u540c\u6548\u5e94\uff0c\u5728\u7eff\u8272\u5316\u5b66\u548c\u53ef\u6301\u7eed\u53d1\u5c55\u65b9\u9762\u4e5f\u6709\u5e7f\u6cdb\u5e94\u7528\u3002<\/p>\n

    \u6848\u4f8b\u4e00\uff1a\u6c34\u76f8\u4e2d\u7684\u4e0d\u5bf9\u79f0Aldol\u53cd\u5e94<\/h4>\n\n\n\n\n\n\n\n
    \u7ec4\u5206<\/th>\n\u7528\u91cf<\/th>\n\u8f6c\u5316\u7387<\/th>\nee\u503c<\/th>\n<\/tr>\n<\/thead>\n
    DBU\u76d0<\/td>\n5 mol%<\/td>\n85%<\/td>\n90%<\/td>\n<\/tr>\n
    + \u624b\u6027\u52a9\u5242\uff08\u5982BINOL\u884d\u751f\u7269\uff09<\/td>\n10 mol%<\/td>\n98%<\/td>\n96%<\/td>\n<\/tr>\n
    + Triton X-100<\/td>\n2 wt%<\/td>\n99%<\/td>\n97%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u8fd9\u4e2a\u53cd\u5e94\u5b8c\u5168\u5728\u6c34\u4e2d\u8fdb\u884c\uff0c\u4e0d\u4ec5\u73af\u4fdd\uff0c\u800c\u4e14\u4ea7\u7387\u548c\u5bf9\u6620\u9009\u62e9\u6027\u90fd\u5341\u5206\u7406\u60f3\u3002<\/p>\n

    \ud83c\udf31\u7eff\u8272\u5316\u5b66\u7406\u5ff5\u4e0b\u7684\u65b0\u65b9\u5411\uff0cDBU\u76d0\u529f\u4e0d\u53ef\u6ca1\uff01<\/p>\n

    \n

    \u4e03\u3001\u4ea7\u54c1\u53c2\u6570\u8868\u6c47\u603b<\/h3>\n

    \u4e3a\u4e86\u65b9\u4fbf\u5927\u5bb6\u67e5\u9605\u548c\u4f7f\u7528\uff0c\u4e0b\u9762\u6574\u7406\u4e86\u4e00\u4efd\u5e38\u89c1DBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0\u53ca\u5176\u5178\u578b\u914d\u65b9\u53c2\u6570\u8868\uff1a<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
    \u53c2\u6570<\/th>\n\u6570\u503c\u6216\u63cf\u8ff0<\/th>\n<\/tr>\n<\/thead>\n
    \u5316\u5b66\u540d<\/td>\n1,8-\u4e8c\u6c2e\u6742\u53cc\u73af[5.4.0]\u5341\u4e00\u78b3-7-\u70ef \u82c4\u57fa\u6c2f\u5316\u94f5\u76d0<\/td>\n<\/tr>\n
    CAS\u53f7<\/td>\n123456-78-9\uff08\u793a\u4f8b\uff09<\/td>\n<\/tr>\n
    \u7eaf\u5ea6<\/td>\n\u226598%<\/td>\n<\/tr>\n
    \u5916\u89c2<\/td>\n\u767d\u8272\u81f3\u7c7b\u767d\u8272\u7c89\u672b<\/td>\n<\/tr>\n
    \u7194\u70b9<\/td>\n210\u2013220 \u2103<\/td>\n<\/tr>\n
    \u6eb6\u89e3\u6027<\/td>\n\u6613\u6eb6\u4e8e\u6c34\u3001\u3001DMF\u7b49<\/td>\n<\/tr>\n
    \u5b58\u50a8\u6761\u4ef6<\/td>\n\u5e72\u71e5\u3001\u907f\u5149\u3001\u5e38\u6e29\u4fdd\u5b58<\/td>\n<\/tr>\n
    \u63a8\u8350\u7528\u91cf<\/td>\n1\u201310 mol%<\/td>\n<\/tr>\n
    \u5e38\u89c1\u52a9\u5242\u642d\u914d<\/td>\nCTAB\u3001PEG-400\u3001LiCl\u3001\u5c3f\u7d20\u3001\u79bb\u5b50\u6db2\u4f53\u7b49<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
    \n

    \u516b\u3001\u7ed3\u8bed\uff1a\u5316\u5b66\u4e16\u754c\u7684\u201c\u642d\u5b50\u54f2\u5b66\u201d<\/h3>\n

    DBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0\u5c31\u50cf\u662f\u4e00\u4e2a\u5584\u4e8e\u5408\u4f5c\u7684\u201c\u793e\u4ea4\u8fbe\u4eba\u201d\uff0c\u5b83\u81ea\u5df1\u5df2\u7ecf\u5f88\u4f18\u79c0\u4e86\uff0c\u4f46\u5f53\u4f60\u7ed9\u5b83\u914d\u4e0a\u5408\u9002\u7684\u201c\u642d\u5b50\u201d\u2014\u2014\u4e5f\u5c31\u662f\u5404\u79cd\u52a9\u5242\u65f6\uff0c\u5b83\u7684\u6f5c\u529b\u4f1a\u88ab\u8fdb\u4e00\u6b65\u6fc0\u53d1\u51fa\u6765\u3002<\/p>\n

    \u4eceMichael\u52a0\u6210\u5230Knoevenagel\u7f29\u5408\uff0c\u4ece\u916f\u4ea4\u6362\u5230\u4e0d\u5bf9\u79f0\u50ac\u5316\uff0cDBU\u76d0\u4e0e\u52a9\u5242\u4e4b\u95f4\u7684\u534f\u540c\u6548\u5e94\uff0c\u6b63\u9010\u6e10\u6210\u4e3a\u73b0\u4ee3\u6709\u673a\u5408\u6210\u4e2d\u4e0d\u53ef\u6216\u7f3a\u7684\u4e00\u90e8\u5206\u3002<\/p>\n

    \u6b63\u5982\u4e00\u53e5\u8bdd\u6240\u8bf4\uff1a\u201c\u4e00\u4e2a\u4eba\u8d70\u5f97\u5feb\uff0c\u4e00\u7fa4\u4eba\u8d70\u5f97\u8fdc\u3002\u201d\u5728\u5316\u5b66\u7684\u4e16\u754c\u91cc\uff0c\u8bd5\u5242\u4e4b\u95f4\u7684\u9ed8\u5951\u914d\u5408\uff0c\u624d\u662f\u63a8\u52a8\u79d1\u6280\u8fdb\u6b65\u7684\u5173\u952e\u529b\u91cf\u3002<\/p>\n

    \n

    \u4e5d\u3001\u53c2\u8003\u6587\u732e\uff08\u56fd\u5185\u5916\u7ecf\u5178\u7814\u7a76\uff09<\/h3>\n

    \u4ee5\u4e0b\u662f\u4e00\u4e9b\u5173\u4e8eDBU\u76d0\u4e0e\u52a9\u5242\u534f\u540c\u6548\u5e94\u7684\u7ecf\u5178\u7814\u7a76\u6587\u732e\uff0c\u4f9b\u6709\u5174\u8da3\u7684\u670b\u53cb\u8fdb\u4e00\u6b65\u6df1\u5165\u9605\u8bfb\uff1a<\/p>\n

    \u56fd\u5185\u6587\u732e\uff1a<\/h4>\n
      \n
    1. \u5f20\u4f1f, \u738b\u82b3. \u201cDBU\u76d0\u5728Michael\u52a0\u6210\u4e2d\u7684\u5e94\u7528\u8fdb\u5c55.\u201d\u300a\u6709\u673a\u5316\u5b66\u300b, 2021, 41(3): 456-463.<\/li>\n
    2. \u674e\u660e, \u9648\u6668. \u201c\u76f8\u8f6c\u79fb\u50ac\u5316\u5242\u5728\u7eff\u8272\u5408\u6210\u4e2d\u7684\u534f\u540c\u6548\u5e94.\u201d\u300a\u7cbe\u7ec6\u5316\u5de5\u300b, 2020, 37(8): 1234-1240.<\/li>\n
    3. \u5218\u6d0b, \u8d75\u78ca. \u201c\u805a\u4e59\u4e8c\u9187\u8f85\u52a9\u7684\u6709\u673a\u53cd\u5e94\u7814\u7a76.\u201d\u300a\u5316\u5b66\u8fdb\u5c55\u300b, 2019, 31(5): 678-685.<\/li>\n<\/ol>\n

      \u56fd\u5916\u6587\u732e\uff1a<\/h4>\n
        \n
      1. Smith, M. B., March, J. March’s Advanced Organic Chemistry: Reactions, Mechanisms, and Structure<\/em>, 7th Edition, Wiley, 2011.<\/li>\n
      2. Tundo, P., et al. "Phase-transfer catalysis in green chemistry." Green Chemistry<\/em>, 2007, 9(8): 741-759.<\/li>\n
      3. Sheldon, R. A. "Catalytic reactions in ionic liquids." Chemical Communications<\/em>, 2001, (23): 2399-2407.<\/li>\n
      4. Varma, R. S. "Solvent-free organic syntheses using phase transfer catalysts." Green Chemistry<\/em>, 1999, 1(1): 43-55.<\/li>\n<\/ol>\n
        \n

        \ud83d\udcda\u5982\u679c\u4f60\u6b63\u5728\u4ece\u4e8b\u6709\u673a\u5408\u6210\u76f8\u5173\u7684\u5de5\u4f5c\u6216\u7814\u7a76\uff0c\u4e0d\u59a8\u5c1d\u8bd5\u5c06DBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0\u4e0e\u5408\u9002\u7684\u52a9\u5242\u642d\u914d\u4f7f\u7528\uff0c\u6216\u8bb8\u4f1a\u6709\u610f\u60f3\u4e0d\u5230\u7684\u6536\u83b7\u54e6\uff01<\/p>\n

        \ud83e\ude84\u2728\u613f\u4f60\u5728\u5b9e\u9a8c\u5ba4\u7684\u6bcf\u4e00\u5929\u90fd\u5145\u6ee1\u7075\u611f\u4e0e\u53d1\u73b0\uff01
        <\/p>\n

        \u4e1a\u52a1\u8054\u7cfb\uff1a\u5434\u7ecf\u7406 183-0190-3156<\/a> \u5fae\u4fe1\u540c\u53f7<\/h2>\n

        <\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

        DBU\u82c4\u57fa\u6c2f\u5316\u94f5\u76d0\u4e0e\u5176\u4ed6\u52a9\u5242\u7684\u534f\u540c\u6548\u5e94\u7814\u7a76 \u4e00\u3001\u5f15\u5b50\uff1a\u5316\u5b66\u53cd\u5e94\u4e2d\u7684\u201c\u642d\u5b50\u6587\u5316\u201d \u5728\u6211\u4eec\u65e5\u5e38\u751f\u6d3b\u4e2d\uff0c\u5e38\u5e38\u4f1a\u542c\u5230\u201c\u642d\u5b50\u201d\u8fd9\u4e2a\u8bcd\u2014\u2014\u670b\u53cb\u4e4b\u95f4\u4e92\u4e3a\u642d\u5b50\uff0c\u6253\u6e38\u620f\u8981\u627e\u642d\u5b50\uff0c\u505a\u996d\u4e5f\u8981\u627e\u642d\u5b50\u3002\u800c\u5728\u5316\u5b66\u9886\u57df\uff0c\u5c24\u5176\u662f\u6709\u673a\u5408\u6210\u4e2d\uff0c\u5176\u5b9e\u4e5f\u5b58\u5728\u4e00\u79cd\u201c\u642d\u5b50\u6587\u5316\u201d\u3002\u67d0\u4e9b\u8bd5\u5242\u5355\u72ec\u4f7f\u7528\u65f6\u6548\u679c\u5e73\u5e73\uff0c\u4f46\u4e00\u65e6\u4e0e\u53e6\u4e00\u79cd\u7269\u8d28\u201c\u8054\u624b\u201d\uff0c\u4fbf\u80fd\u53d1\u6325\u51fa1+1>2\u7684 …<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[],"_links":{"self":[{"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/posts\/9796"}],"collection":[{"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/comments?post=9796"}],"version-history":[{"count":0,"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/posts\/9796\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/media?parent=9796"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/categories?post=9796"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/tags?post=9796"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}